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MER/SKY (AA 716-765), (pTyr749) antibody

This Rabbit Polyclonal antibody specifically detects in IHC, WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN1532058

Quick Overview for MER/SKY (AA 716-765), (pTyr749) antibody (ABIN1532058)

Target

MER/SKY

Reactivity

Human, Mouse, Rat

Host

  • 9
Rabbit

Clonality

  • 9
Polyclonal

Conjugate

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Un-conjugated

Application

Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • Binding Specificity

    AA 716-765, pTyr749

    Specificity

    MER/SKY (Phospho-Tyr749/681) Antibody detects endogenous levels of MER/SKY only when phosphorylated at Tyr749/681.

    PhosphorylationH:Y749/681 M:Y744/671 R:Y744/671

    Purification

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    Purity

    > 95 %

    Immunogen

    The antiserum was produced against synthesized peptide derived from human MER/SKY around the phosphorylation site of Tyr749/681.

    Isotype

    IgG
  • Application Notes

    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

    Comment

    Unigene-Number: Hs.306178, Hs.677398, Hs.381282 (NCBI Gene Symbol: MERTK)

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Stable at -20°C for at least 1 year.

    Expiry Date

    12 months
  • Target

    MER/SKY

    Background

    Synonyms: C-mer, Receptor tyrosine kinase MerTK/ Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase DTK, Protein-tyrosine kinase byk

    NCBI Gene Symbol: MERTK

    Molecular Weight

    110 kDa

    Gene ID

    10461, 7301

    OMIM

    268000

    UniProt

    Q12866, Q06418
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